The replacement of higher-calorie sweeteners with lower- and/or no-calorie alternatives may facilitate weight loss or weight maintenance by helping to reduce energy intake. Paige Miller and Vanessa Perez reviewed and evaluated several studies that examined the relation between lower-calorie sweeteners (from foods, beverages and tabletop sweeteners) and bodyweight and body composition. Several well-conducted studies indicated that individuals who substituted lower-calorie sweetener options for their regular-calorie versions experienced modest weight loss. This may be a useful dietary tool/strategy to improve overall compliance and success with weight loss and/or weight maintenance programs.
[Miller, Paige E., and Vanessa Perez. “Low-calorie sweeteners and body weight and composition: a meta-analysis of randomized controlled trials and prospective cohort studies.” The American Journal of Clinical Nutrition 100.3 (2014): 765-777.]