New research suggests that drinking sodas and eating processed foods, both of which contain high levels of phosphates, may accelerate the aging process. M. Shawkat Razzaque, M.D., Ph.D., of the Department of Oral Medicine, Infection and Immunity at the Harvard School of Dental Medicine, and Mutsuko Ohnishi, of the Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences in Japan, studied the effects of high phosphate concentration in three groups of mice.
The first group was missing klotho, a gene that, when absent, causes mice to have toxic amounts of phosphate in their bodies. Those mice lived for eight to 15 weeks.
The second group was missing the klotho gene, as well as a gene called NaPi2a, which, when absent at the same time, substantially lowered the amount of phosphate in their bodies. Those mice lived to 20 weeks.
The third group, like the second group, was missing both the klotho and NaPi2a genes but was also fed a high-phosphate diet. Like the mice in the first group, all of the mice in the third group died by 15 weeks, thus suggesting that phosphate has toxic effects in mice and raising the possibility that it may have a similar effect on humans. Further investigation revealed that high amounts of phosphates accelerate signs of aging and may increase the prevalence and severity of age-related complications, such as chronic kidney disease and cardiovascular calcification. They may also induce severe muscle and skin atrophy.
“Humans need a healthy diet, and keeping the balance of phosphate in the diet may be important for a healthy life and longevity,” said Dr. Razzaque. “Avoid phosphate toxicity, and enjoy a healthy life.”
—Dr. Bob Goldman
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Dr. Robert M. Goldman MD, PhD, DO, FAASP has spearheaded the development of numerous international medical organizations and corporations. Dr. Goldman has served as a Senior Fellow at the Lincoln Filene Center, Tufts University; as an Affiliate at the Philosophy of Education Research Center, Graduate School of Education, Harvard University, He is Clinical Consultant, Department of Obstetrics and Gynecology, Korea Medical University; and Professor, Department of Internal Medicine at the University of Central America Health Sciences, Department of Internal Medicine. Dr. Goldman holds the positions of Visiting Professor, Udayana University School of Medicine, Indonesia; Visiting Professor, Huazhong University of Science & Technology Tong Ji Medical School, China; Visiting Professor, The Wuhan Institute of Science & Technology, China; Visiting Professor at Hainan Medical College, China; and Visiting Professor, School of Anti-Aging, Aesthetics and Regenerative Medicine, UCSI University, Malaysia. Dr. Goldman is a Fellow of the American Academy of Sports Physicians and a Board Diplomat in Sports Medicine and Board Certified in Anti-Aging Medicine. Dr. Goldman is a Fellow of the American Academy of Sports Physicians and a Board Diplomat in Sports Medicine and Board Certified in Anti-Aging Medicine. He has overseen cooperative research agreement development programs in conjunction with such prominent institutions as the American National Red Cross, the US National Aeronautics and Space Administration (NASA), the Department of Defense, and the FDA’s Center for Devices & Radiological Health.
Dr Goldman was awarded the 2012 LifeTime Achievement Award in Medicine &Science. Dr. Goldman is the recipient of the ‘Gold Medal for Science, the Grand Prize for Medicine, the Humanitarian Award, and the Business Development Award. He received honors from Minister of Sports and government Health officials of numerous nations. In 2001, Excellency Juan Antonio Samaranch awarded Dr. Goldman the International Olympic Committee Tribute Diploma for contributions to the development of sport & Olympism.
In addition, Dr. Goldman is a black belt in karate, Chinese weapons expert, and world champion athlete with over 20 world strength records, he has been listed in the Guinness Book of World Records. Some of his past performance records include 13,500 consecutive situps and 321 consecutive handstand pushups. Dr. Goldman was an All-College athlete in four sports, a three time winner of the John F. Kennedy (JFK) Physical Fitness Award, was voted Athlete of the Year, was the recipient of the Champions Award, and was inducted into the World Hall of Fame of Physical Fitness. Dr. Goldman was awarded the Healthy American Fitness Leader Award from the President’s Council on Physical Fitness & Sports and U.S. Chamber of Commerce. Dr. Goldman is Chairman of the International Medical Commission overseeing sports medicine committees in over 184 nations. He has served as a Special Advisor to the President’s Council on Physical Fitness & Sports. He is founder and international President Emeritis of the National Academy of Sports Medicine and the cofounder and Chairman of the American Academy of Anti-Aging Medicine (A4M). Dr. Goldman visits an average of 20 countries annually to promote brain research and sports medicine programs.